{"id":2544,"date":"2018-05-24T16:57:32","date_gmt":"2018-05-24T14:57:32","guid":{"rendered":"https:\/\/orgveda.sajthost.com\/?page_id=2544"},"modified":"2025-01-20T13:36:56","modified_gmt":"2025-01-20T12:36:56","slug":"isabgol-indijska-bokvica","status":"publish","type":"product","link":"https:\/\/orgveda.sajthost.com\/?product=isabgol-indijska-bokvica","title":{"rendered":"Isabgol indijska bokvica"},"content":{"rendered":"

\u010cista i zdrava creva!
\nIsabgol \u2013 indijska bokvica<\/h2>\n

TOKSINI U CREVIMA \u2013 IZVOR SAVREMENIH HRONI\u010cNIH NEZARAZNIH BOLESTI<\/h4>\n

\u0160TA JE TO AMA?<\/h2>\n

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Ama je op\u0161ti naziv koji ajur veda koristi za sve toksine koji nastaju u telu. Kada je varenje iz bilo kog razloga oslabljeno \u2013 usled stresa, pogre\u0161nih navika u ishrani, radu, odmaranju, vremenskih \"Isabgol\"prilika… hrana se ne vari u potpunosti. Jedan deo hrane koju pojedemo se svari i pretvara u korisna tkiva i energiju, drugi deo se izbaci prirodnim tokovima pra\u017enjenja otpadaka, a odre\u0111eni deo ostaje u debelom crevu i tu se nakuplja. Ovi otpaci koji se nakupljaju u debelom crevu i niti se izbacuju, niti se vare, zovu se ama<\/em><\/strong>. Ama je koren i uzrok svih bolesti. Tokom vremena, ama po\u010dinje da truli u debelom crevu i stvara otrovnu i lepljivu supstancu izuzetno neprijatnog mirisa. U prvom i drugom stanju razvoja bolesti (prema ajur vedi), koli\u010dina ame nije velika i ona uglavnom ostaje u debelom crevu. U tre\u0107em stadijumu ona po\u010dinje da se preliva u krv, limfu i kapilarni sistem i tako kru\u017ei telom, tra\u017ee\u0107i slabo mesto, slabu ta\u010dku. U \u010detvrtom stanju, ama se bukvalno prilepi za odre\u0111eni organ ili tkivo (na primer holesterol za krvne sudove) i tu se dalje nakuplja sve dok ne izbije u vidu jasnih simptoma u petom stanju. Kada je ama veoma razvijena u petom stanju bolesti, tada i zapadna, alopatska medicina priznaje da je \u010dovek bolestan i dijagnostikuje:<\/strong> artritis, anginu pektoris, visok holesterol, astmu i hroni\u010dni bronhitis, razne “e\u0161erihije“ i “kandide“ itd<\/strong>. U \u0161estom stanju ama ve\u0107 blokira razne organe, uni\u0161tava tkiva i blokira rad sistema (metastaze raka u raznim delovima tela, pucanje \u010dira na \u017eelucu i sli\u010dno). Dakle, \u010dim se pojavi ama, \u010dovek je ve\u0107 bolestan. Prisustvo ame se mo\u017ee primetiti kao skrama na jeziku, neprijatan zadah iz usta, stolica i urin koji neprijatno miri\u0161u, glavobolja, nedostatak energije i lo\u0161e raspolo\u017eenje itd.<\/strong><\/p>\n

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KAKO ISKORENITI AMU?<\/h3>\n

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Osnovni preduslov da se ama ukloni iz sistema jeste da se oja\u010da probavna vatra, tzv. agni. Kada je vatra varenja jaka, ona spaljuje sve toksine u crevnom sistemu i tkivima.
\nDrugi na\u010din za izbacivanje ame, naro\u010dito ako je prodrla dublje u tkiva, jeste upotreba pro\u010di\u0161\u0107avaju\u0107ih sredstava \u2013 laksativa.<\/p>\n

Postoje dva osnovna tipa biljnih laksativa. Jedni se zovu purgativi i uklju\u010duju biljke kao \u0161to su: sena, rabarbara, leptandra ili krkavina. Oni uglavnom sadr\u017ee gorke principe u obliku antrokina koji stimuli\u0161u peristaltiku intestinalnog trakta, bilo direktno bilo podsticanjem sekrecije \u017eu\u010di kroz jetru ili \u017eu\u010dni mehur.<\/p>\n

Drugi tip laksativa su uljasti i kabasti (lubrikantni) laksativi koji uklju\u010duju biljke kao \u0161to su isabgol i seme lana. Oni su hranljiviji i obi\u010dno nemaju nikakav direktan uticaj na jetru ili \u017eu\u010dnu kesu. Oni pre deluju poput sun\u0111era koji se uve\u0107ava kada apsorbuje te\u010dnost, funkcioni\u0161i\u0107i nalik nekoj vrsti crevne metle.<\/p>\n

Purgativna sredstva su potrebna ljudima koji pate od neredovne stolice uzrokovane kongestijom jetre i \u017eu\u010dne kese koja je obi\u010dno udru\u017eena sa izvesnom dozom toksina u krvi. Oni kojima su potrebni lubrikantni laksativi pate od intestinalne suho\u0107e uzrokovane razli\u010ditim metaboli\u010dkim faktorima koji uklju\u010duju, kako nedostatak hranljivih materija, tako i vi\u0161ak metaboli\u010dke energije.<\/p>\n

\u0160TA JE ISABGOL<\/strong>?<\/strong><\/p>\n

\"Isabgol\"<\/p>\n

Isabgol je indijski naziv za semeni omota\u010d biljke Plantago<\/em> ovata<\/em> to jest Plantago<\/em> psyllium<\/em>, koja je veoma sli\u010dna na\u0161oj doma\u0107oj bokvici, samo \u0161to raste u jugoisto\u010dnoj Aziji. Mekinje psilijuma smatraju se u ajurvedi najboljim crevnim podmaziva\u010dem i svojevrsnom metlom za creva. Ove mekinje upijaju koli\u010dinu vode i crevnog sadr\u017eaja mnogo puta ve\u0107u nego \u0161to su one same te\u0161ke, \u010dime re\u0161avaju razli\u010dite crevne probleme koji uklju\u010duju i konstipaciju i dijareju.<\/p>\n

KO TREBA DA KORISTI ISABGOL?<\/h4>\n

Isabgol deluje kao blagi laksativ, diuretik, protivupalno i omek\u0161avaju\u0107e. Osobe koje pate od hroni\u010dnog zatvora, hroni\u010dne dijareje, dizenterije, kolitisa, Kronove bolesti, gastritisa, \u010dira, uretritisa i cistitisa<\/strong> mogu da osete zna\u010dajne dobrobiti upotrebom isabgola.<\/p>\n

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KAKO KORISTITI ISABGOL:<\/h3>\n

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1. Zatvor, slabo pra\u017enjenje<\/strong>
\nIsabgol sadr\u017ei znatnu koli\u010dinu kako rastvorljivih, tako i nerastvorljivih biljnih vlakana \u0161to je veoma va\u017eno za osobe koje pate od zatvora. Mekinje indijske bokvice upijaju veliku koli\u010dinu vode, bubre u crevima, podmazuju ih i nose sa sobom talog isu\u0161ene stolice.
\nPome\u0161ajte dve ka\u0161i\u010dice isabgola sa 100 ml toplog kravljeg mleka i odmah popijte, da mekinje ne nabubre u \u010da\u0161i. Uzimajte ovo uve\u010de, pre spavanja.<\/strong><\/p>\n

2. Dijareja<\/strong>
\nIsabgol deluje hlade\u0107e i protivupalno, u crevima upija i sa sobom nosi veliku koli\u010dinu organizama, me\u0111u kojima su i patogeni, izaziva\u010di razli\u010ditih tegoba pra\u0107enih prolivom \u2013 dizenterije, kolitisa, Kronove bolesti, stoma\u010dnog gripa… Za zaustavljanje ovih simptoma, Isabgol je najbolje koristiti sa sve\u017eim kiselim mlekom<\/strong> ili sve\u017eim jogurtom<\/strong>. Na ovaj na\u010din creva se kolonizuju probiotskim bakterijama u pravilnoj razmeri, \u0161to omogu\u0107ava njihov normalan rad.
\nPome\u0161ajte dve ka\u0161i\u010dice isabgola sa dve supene ka\u0161ike sve\u017eeg kiselog mleka i pojedite ovo posle doru\u010dka i posle ru\u010dka (uve\u010de nije dobro koristiti kisele mle\u010dne proizvode).<\/strong><\/p>\n

3. \u010ci\u0161\u0107enje debelog creva<\/strong>
\nZahvaljuju\u0107i svojoj higroskopnoj prirodi, isabgol tokom kretanja kroz creva upija i sakuplja \u0161tetne mikroorganizme, toksine i otpatke, koji se u ajurvedi jednim imenom nazivaju “ama“. Ova otrovna i lepljiva supstanca naj\u010de\u0161\u0107e se zalepi za zidove debelog creva odakle tokom vremena prelazi u krvotok i uzrokuje razli\u010dite probleme. \u010ci\u0161\u0107enjem ame, zdravlje, raspolo\u017eenje i izgled se popravljaju.
\nPome\u0161ajte dve ka\u0161i\u010dice isabgola sa 200 ml tople vode i pijte uve\u010de pre spavanja, svakog drugog dana tokom mesec dana.<\/strong><\/p>\n

4. Gastritis, heliko bakterija<\/strong>
\nVi\u0161ak kiseline u \u017eelucu dovodi do raznih neprijatnosti, a ako traje dugo mo\u017ee dovesti i do \u010dira u organima za varenje. Omek\u0161avaju\u0107a i sluzasta svojstva isabgola ovde mogu da “u\u010dine \u010duda“.
\nPome\u0161ajte dve ka\u0161i\u010dice isabgola sa 100 ml vode (ne tople ili vru\u0107e) i popijte posle jela, dva puta dnevno. Isabgol \u0107e upiti vi\u0161ak kiseline i bakterija, smiriti pita do\u0161u.<\/strong><\/p>\n

5. \u010cir na \u017eelucu i dvanaestercu<\/strong>
\nKod ovih stanja mehanizam delovanja isabgola je isti kao i kod vi\u0161ka kiseline. S obzirom na \u010dinjenicu da \u010dir predstavlja ozbiljno o\u0161te\u0107enje sluznih membrana, potrebno je koristiti dodatna sredstva za zarastanje i smanjenje korozije. Stoga, osim saveta za upotrebu pod brojem 4 (gastritis) dodajte i savet za upotrebu pod brojem jedan, to jest uve\u010de pre spavanja, sa toplim kravljim mlekom.<\/p>\n

6. Kolitis, Kronova bolest<\/strong>
\nU ovim slu\u010dajevima ishrana je izuzetno bitna, treba izbegavati te\u0161ku hranu. Isabgol treba uzimati sa lasijem \u2013 me\u0161avinom sve\u017eeg kiselog mleka i vode. Pome\u0161ajte dve supene ka\u0161ike sve\u017eeg kiselog mleka i 100 ml vode, dodajte \u00bc ka\u0161i\u010dice sve\u017ee mlevenog indijskog (rimskog, \u0111ira) kima i prstohvat sve\u017ee struganog muskatnog oraha. Sve ovo dobro izme\u0161ajte dok ne dobijete homogen napitak. U ovo dodajte dve ka\u0161i\u010dice isabgola i popijte dva puta dnevno, posle jela.<\/p>\n

7. Gojaznost<\/strong>
\nPrejedanje usled stresa i nervoze, preterana upotreba kalori\u010dne i rafinisane hrane, bez biljnih vlakana, naj\u010de\u0161\u0107i su uzroci gojaznosti danas. Isabgol donosi obilje biljnih vlakana, kako onih nerastvorljivih, koji dugo odr\u017eavaju ose\u0107aj sitosti i punine u stomaku, tako i rastvorljivih, koja sakupljaju masno\u0107e, \u017eu\u010d i druge otpatke koji slabe razmenu materija i dovode do gojaznosti.
\nPome\u0161ajte ka\u0161i\u010dicu isabgola, ka\u0161i\u010dicu limunovog soka i 100 ml tople vode i popijte pola sata pre doru\u010dka i pola sata pre ru\u010dka.<\/strong> \u017dudnja za hranom bi\u0107e daleko manja, a samim tim i unos nepotrebnih kalorija. Svaki put kada osetite glad na nervnoj bazi, popijte ovaj napitak kako biste smirili stres, a ujedno i spre\u010dili gojenje.<\/strong><\/p>\n

8. Hemoroidi, fistule<\/strong>
\nKao \u0161to je ve\u0107 re\u010deno, biljna vlakna i laksativna svojstva isabgola doprinose lak\u0161em i bezbolnijem pra\u017enjenju creva, bez naprezanja i suvo\u0107e. Na taj na\u010din spre\u010dava se pucanje krvnih sudova. Osim toga, isabgol je blago oporog ukusa \u0161to donekle poma\u017ee zarastanju fistule i zaustavljanju krvarenja.
\nPome\u0161ajte dve ka\u0161i\u010dice isabgola sa 200 ml tople vode ili toplog kravljeg mleka i popijte uve\u010de pre spavanja, dok se stanje ne popravi.<\/strong><\/p>\n

9. Holesterol, dijabetes, visok pritisak<\/strong>
\nSavremena istra\u017eivanja pokazala su da ishrana bogata biljnim vlaknima smanjuje apsorpciju masti i \u0161e\u0107era. Zbog toga mnogi lekari i nutricionisti savetuju pove\u0107ani unos biljnih vlakana, naro\u010dito rastvorljivih, kako bi se smanjile ili spre\u010dile posledice povi\u0161enog nivoa holesterola ili glukoze. Ni\u017ei nivo holesterola povezan je i sa ni\u017eim krvnim pritiskom i zdravijim srcem, a na srce i pritisak blagotvorno deluje i uklanjanje konstipacije i toksina iz debelog creva.
\nNa\u010din uzimanja kod nekog od ovih stanja zavisi od telesne gra\u0111e i stanja zdravlja osobe. Pogledajte neki od na\u010dina opisanih navi\u0161e, pa izaberite onaj koji je najprikladniji.<\/strong><\/p>\n

Ne\u017eeljena dejstva:<\/strong>
\nNije dobro uzimati isabgol kod lenjih creva, a to je stanje kada su creva puna sadr\u017eaja, ali se ne kre\u0107u i hrana u njima stoji i ne vari se. Tako\u0111e, osobe koje imaju slab Agni \u2013 oganj varenja u \u017eelucu odnosno manjak kiseline, ne bi trebale da koriste lubrikantne laksative u koje spada i isabgol.<\/p>\n

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SAVREMENA NAU\u010cNA ISTRA\u017dIVANJA I ISABGOL:<\/strong><\/p>\n

J Evid Based Integr Med.<\/a>\u00a02018 Jan-Dec;23:2515690X18763294. doi: 10.1177\/2515690X18763294.<\/p>\n

1.\u00a0\u00a0 Comparing the Effect of\u00a0Psyllium\u00a0Seed on Gastroesophageal Reflux Disease With Oral Omeprazole in Patients With Functional Constipation.<\/h3>\n

Hosseini M<\/a>1<\/sup>,\u00a0Salari R<\/a>1<\/sup>,\u00a0Akbari Rad M<\/a>1<\/sup>,\u00a0Salehi M<\/a>1<\/sup>,\u00a0Birjandi B<\/a>1<\/sup>,\u00a0Salari M<\/a>1<\/sup>.<\/p>\n

Author information<\/a><\/h3>\n

Abstract<\/h3>\n

Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. Several studies have been carried out on the treatment of symptoms associated with GERD. The present study aimed to compare the effect of\u00a0Psyllium\u00a0seed and oral omeprazole on GERD in patients with functional constipation. In this trial, 132 patients were divided into 2 groups. The impact of omeprazole and\u00a0Psylliumseed on the treatment and recurrence of GERD was studied. Among the patients, the rate of response to treatment was 89.2% (n = 58) in the\u00a0Psyllium\u00a0seed group, while in omeprazole group, it was 94% (n = 63; P = .31). The recurrence rates of\u00a0Psyllium\u00a0seed and omeprazole groups were 24.1% (n =14) and 69.8% (n = 44), respectively ( P < .001). The results showed that treatment of functional constipation by\u00a0Psylliumseed in patients with GERD leads to improvement of GERD and its recurrences in comparison with omeprazole.<\/p>\n

KEYWORDS:<\/h4>\n

GERD; functional constipation; gastroesophageal reflux disease; omeprazole;\u00a0psyllium\u00a0seed<\/p>\n

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J Chiropr Med.<\/a>\u00a02017 Dec;16(4):289-299. doi: 10.1016\/j.jcm.2017.05.005. Epub 2017 Oct 25.<\/p>\n

Dietary Fiber Is Beneficial for the Prevention of Cardiovascular Disease: An Umbrella Review of Meta-analyses.<\/h3>\n

McRae MP<\/a>1<\/sup>.<\/p>\n

Author information<\/a><\/h3>\n

Abstract<\/h3>\n

OBJECTIVE:<\/h4>\n

The purpose of this study was to review previously published meta-analyses on the effectiveness of dietary fiber on cardiovascular disease.<\/p>\n

METHODS:<\/h4>\n

An umbrella review of all published meta-analyses was performed. A PubMed search from January 1, 1980, to January 31, 2017, was conducted using the following search strategy: (fiber OR glucan OR\u00a0psyllium\u00a0OR fructans) AND (meta-analysis OR systematic review). Only English-language publications that provided quantitative statistical analysis on cardiovascular disease, lipid concentrations, or blood pressure were retrieved.<\/p>\n

RESULTS:<\/h4>\n

Thirty-one meta-analyses were retrieved for inclusion in this umbrella review, and all meta-analyses comparing highest versus lowest dietary fiber intake reported statistically significant reductions in the relative risk (RR) of cardiovascular disease mortality (RR = 0.77-0.83), as well as the incidences of cardiovascular disease (RR = 0.72-0.91), coronary heart disease (RR = 0.76-0.93), and stroke (RR = 0.83-0.93). Meta-analyses on supplementation studies using \u03b2-glucan or\u00a0psyllium\u00a0fibers<\/strong> also reported statistically significant reductions in both total serum and low-density lipoprotein cholesterol concentrations.<\/p>\n

CONCLUSION:<\/h4>\n

This review suggests that individuals consuming the highest amounts of dietary fiber intake can significantly reduce their incidence and mortality from cardiovascular disease. Mechanistically, these beneficial effects may be due to dietary fibers’ actions on reducing total serum and low-density lipoprotein cholesterol concentrations between 9.3 to 14.7 mg\/dL and 10.8 to 13.5 mg\/dL, respectively.<\/p>\n

KEYWORDS:<\/h4>\n

Blood Pressure; Cardiovascular Diseases; Cholesterol; Coronary Heart Disease; Dietary Fiber; Meta-analysis; Stroke<\/p>\n

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J Chiropr Med.<\/a>\u00a02018 Mar;17(1):44-53. doi: 10.1016\/j.jcm.2017.11.002. Epub 2018 Mar 1.<\/p>\n

Dietary Fiber Intake and Type 2 Diabetes Mellitus: An Umbrella Review of Meta-analyses.<\/h3>\n

McRae MP<\/a>1<\/sup>.<\/p>\n

Author information<\/a><\/h3>\n

Abstract<\/h3>\n

OBJECTIVE:<\/h4>\n

The purpose of this study was to review previously published meta-analyses on the effectiveness of dietary fiber on type 2 diabetes.<\/p>\n

METHODS:<\/h4>\n

An umbrella review of all published meta-analyses was performed. A PubMed search from January 1, 1980, to April 30, 2017, was conducted using the following search strategy: (fiber OR glucan OR\u00a0psyllium<\/strong>) AND (meta-analysis OR systematic review). Only English-language publications that provided quantitative statistical analysis on type 2 diabetes, fasting blood glucose concentrations, or glycosylated hemoglobin were retrieved.<\/p>\n

RESULTS:<\/h4>\n

Sixteen meta-analyses were retrieved for inclusion in this umbrella review. In the meta-analyses comparing highest versus lowest dietary fiber intake, there was a statistically significant reduction in the relative risk (RR) of type 2 diabetes (RR = 0.81-0.85), with the greatest benefit coming from cereal fibers (RR = 0.67-0.87). However, statistically significant heterogeneity was observed in all of these meta-analyses. In the meta-analyses of supplementation studies using \u03b2-glucan or\u00a0psyllium\u00a0fibers on type 2 diabetic participants, statistically significant reductions were identified in both fasting blood glucose concentrations and glycosylated hemoglobin percentages.<\/p>\n

CONCLUSION:<\/h4>\n

This review suggests that those consuming the highest amounts of dietary fiber, especially cereal fiber, may benefit from a reduction in the incidence of developing type 2 diabetes. There also appears to be a small reduction in fasting blood glucose concentration, as well as a small reduction in glycosylated hemoglobin percentage for individuals with type 2 diabetes who add \u03b2-glucan or\u00a0psyllium\u00a0to their daily dietary intake.<\/p>\n

KEYWORDS:<\/h4>\n

Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fiber; Hemoglobin A, Glycosylated<\/p>\n

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Br J Nutr.<\/a>\u00a02017 Nov;118(9):661-672. doi: 10.1017\/S0007114517002586.<\/p>\n

Supplemental\u00a0psyllium\u00a0fibre regulates the intestinal barrier and inflammation in normal and colitic mice.<\/h3>\n

Ogata M<\/a>1<\/sup>,\u00a0Ogita T<\/a>2<\/sup>,\u00a0Tari H<\/a>3<\/sup>,\u00a0Arakawa T<\/a>3<\/sup>,\u00a0Suzuki T<\/a>1<\/sup>.<\/p>\n

Author information<\/a><\/h3>\n

Abstract<\/h3>\n

Our previous study demonstrated that supplemental\u00a0psyllium\u00a0fibre increased cytoprotective heat-shock protein (Hsp) 25 levels in the intestinal cells of mice. Here, we examined the effect of\u00a0psyllium\u00a0fibre on colonic gene and protein expression and faecal microbiota in normal and colitic mice to improve the understanding of the preventive role of the supplement. DNA microarray analysis revealed that a 10 %\u00a0psylliumfibre diet administered for 5 d up-regulated eleven extracellular matrix (ECM)-associated genes, including collagens and fibronectins, in normal mice. Acute colitis was induced using dextran sodium sulphate (DSS) in mice that were administered a pre-feeding 5 to 10 %\u00a0psylliumfibre diet for 5 d.\u00a0Psyllium\u00a0fibre partially ameliorated or resolved the DSS-induced colon damage and inflammation characterised by body weight loss, colon shortening, increased levels of pro-inflammatory cytokines and decreased tight junction protein expression in the colon. Analysis of faecal microbiota using denaturing gradient gel electrophoresis of the PCR-amplified 16S rRNA gene demonstrated that\u00a0psylliumfibre affected the colonic microbiota. Intestinal permeability was evaluated by growing intestinal Caco-2 cell monolayers on membrane filter supports coated with or without fibronectin and collagen. Cells grown on collagen and fibronectin coating showed higher transepithelial electrical resistance, indicating a strengthening of barrier integrity. Therefore, increased Hsp25 levels and modification of colonic ECM contribute to the observed\u00a0psyllium-mediated protection against DSS-induced colitis. Furthermore, ECM modification appears to play a role in the strengthening of the colon barrier. In conclusion,\u00a0psyllium\u00a0fibre may be useful in the prevention of intestinal inflammatory diseases.<\/p>\n

KEYWORDS:<\/h4>\n

DF dietary fibre; DGGE denaturing gradient gel electrophoresis; DSS dextran sodium sulphate; ECM extracellular matrix; FD4 conjugated dextran; GO gene ontology; Hsp heat-shock protein; IBD inflammatory bowel disease; JAM junctional adhesion molecule; LBP lipopolysaccharide-binding protein; TER transepithelial electrical resistance; TJ tight junction; ZO zonula occludens; colI\u03b11 collagen type I\u03b11; Extracellular matrix; Heat-shock protein; Intestinal inflammation;\u00a0Psyllium; Tight junction protein<\/p>\n

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Nutr Metab Cardiovasc Dis.<\/a>\u00a02018 Jan;28(1):3-13. doi: 10.1016\/j.numecd.2017.09.007. Epub 2017 Oct 7.<\/p>\n

The effect of viscous soluble fiber on blood pressure: A systematic review and meta-analysis of randomized controlled trials.<\/h3>\n

Khan K<\/a>1<\/sup>,\u00a0Jovanovski E<\/a>2<\/sup>,\u00a0Ho HVT<\/a>2<\/sup>,\u00a0Marques ACR<\/a>3<\/sup>,\u00a0Zurbau A<\/a>2<\/sup>,\u00a0Mejia SB<\/a>4<\/sup>,\u00a0Sievenpiper JL<\/a>5<\/sup>,\u00a0Vuksan V<\/a>6<\/sup>.<\/p>\n

Author information<\/a><\/h3>\n

Abstract<\/h3>\n

AIMS:<\/h4>\n

Dietary fiber intake, especially viscous soluble fiber, has been established as a means to reduce cardiometabolic risk factors. Whether this is true for blood pressure remains controversial. A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to investigate the effects of viscous soluble fiber supplementation on blood pressure and quantify the effect of individual fibers.<\/p>\n

DATA SYNTHESIS:<\/h4>\n

MEDLINE, Embase, and Cochrane databases were searched. We included RCTs of \u22654-weeks in duration assessing viscous fiber supplementation from five types: \u03b2-glucan from oats and barley, guar gum, konjac, pectin and\u00a0psyllium<\/strong>, on systolic blood pressure (SBP) and diastolic blood pressure (DBP). Study data were pooled using the generic inverse variance method with random effects models and expressed as mean differences (MD) with 95% confidence intervals (CIs). Twenty-two (N\u00a0=\u00a01430) and twenty-one RCTs (N\u00a0=\u00a01343) were included in the final analysis for SBP and DBP, respectively. Viscous fiber reduced SBP (MD\u00a0=\u00a0-1.59\u00a0mmHg [95% CI: -2.72,-0.46]) and DBP (MD\u00a0=\u00a0-0.39\u00a0mmHg [95% CI: -0.76,-0.01]) at a median dose of 8.7\u00a0g\/day (1.45-30\u00a0g\/day) over a median follow-up of 7-weeks. Substantial heterogeneity in SBP (I2<\/sup>\u00a0=\u00a072%, P\u00a0<\u00a00.01) and DBP (I2<\/sup>\u00a0=\u00a067%, P\u00a0<\u00a00.01) analysis occurred. Within the five fiber types, SBP reductions were observed only for supplementation using\u00a0psyllium\u00a0fiber (MD\u00a0=\u00a0-2.39\u00a0mmHg [95% CI: -4.62,-0.17]).<\/p>\n

CONCLUSION:<\/h4>\n

Viscous soluble fiber has an overall lowering effect on SBP and DBP. Inclusion of viscous fiber to habitual diets may have additional value in reducing CVD risk via improvement in blood pressure.<\/p>\n

PROTOCOL REGISTRATION:<\/h4>\n

ClinicalTrials.gov identifier-NCT02670967<\/a>.<\/p>\n

Copyright \u00a9 2017 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.<\/p>\n

KEYWORDS:<\/h4>\n

Blood pressure; Guar gum; Konjac; Meta-analysis; Pectin;\u00a0Psyllium; Viscous soluble fiber; \u03b2-Glucan<\/p>\n

 <\/p>\n

J Complement Integr Med.<\/a>\u00a02017 Mar 21;14(2). pii: \/j\/jcim.2017.14.issue-2\/jcim-2015-0075\/jcim-2015-0075.xml. doi: 10.1515\/jcim-2015-0075.<\/p>\n

Cytokine changes in gastric and colonic epithelial cell in response to Planta ovata extract.<\/h3>\n

Yakoob J<\/a>,\u00a0Jafri W<\/a>,\u00a0Mehmood MH<\/a>,\u00a0Abbas Z<\/a>,\u00a0Tariq K<\/a>.<\/p>\n

Abstract<\/h3>\n

Background Psyllium (Planta ovata, Ispaghul) seed and husk are used for treatment of altered bowel habit, i.\u2006e. constipation and diarrhea. We studied the effect of Ispaghul extract on secretion of interleukin-1 beta (IL-1\u03b2) by AGS (ATCC CRL 1739) and SW480 (ATCC CCL-227) epithelial cell lines and determined whether Ispaghul extract has an effect on IL-1\u03b2 secretion by Helicobacter pylori (H. pylori)-stimulated AGS cell and Escherichia coli K-12 (E. coli K-12)-stimulated SW480 cells in vitro. Methods The AGS cells and SW480 cells were pretreated with Ispaghul extract in concentrations, i.\u2006e. 3.5 and 7\u2006\u03bcg\/mL prior to infection with H. pylori and E. coli K-12. Results DNA fragmentation in AGS and SW480 cells treated with Ispaghul extract was not significant (2.3\u00b10.8\u2006%) compared with untreated cells (2.2\u00b10.6\u2006%). Ispaghul extract decreased the H. pylori-stimulated secretion of IL-1\u03b2 by AGS cell (p<0.0001). This effect did not increase as the concentration of extract was increased. Ispaghul extract also decreased E. coli K-12-stimulated IL-1\u03b2 secretion by SW480 cell (p<0.0001). This effect increased as the concentration of extracts was increased. Conclusions Ispaghul extract had an effect on stimulated secretion of IL-1\u03b2 by the AGS and SW480 cell. It decreased pro-inflammatory reaction from both cell lines stimulated by bacteria.<\/p>\n

KEYWORDS:<\/h4>\n

AGS cell; E. coli K-12; H. pylori; Ispaghul husk; SW480; interleukin-1\u03b2<\/p>\n","protected":false},"excerpt":{"rendered":"

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